Fibrinogen (Factor I) (Last Updated - 2/27/2005)
-gets activated to form fibrin (Factor Ia) via catalysis by calcium (Factor IV) & thrombin (Factor IIa)
-click here to view an image of the clotting cascade
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References:
Goodman & Gilman's: The Pharmacologic Basis Of Therapeutics - 10th Edition - 2001. Chapter 55.